Scientists at the laboratory are investigating how long-term biochemical stress contributes to cellular aging and tissue degeneration. Current studies focus on mitochondrial dysfunction, oxidative signaling imbalance, and cumulative protein instability. The research may contribute to future preventative therapies aimed at improving long-term cellular resilience and healthy aging.
Scientists at the Alder Molecular Biochemistry Laboratory have identified a previously uncharacterized enzyme involved in regulating oxidative stress responses within human cells. The discovery may improve understanding of how cells adapt to environmental and metabolic stress conditions associated with chronic disease progression. The research team is now investigating how modulation of the enzyme’s activity could […]